HTA Ltd. is an international consultancy partnering with leading pharmaceutical and medical devices manufacturers, investors and funds, with projects in Europe, Africa, Middle East, and Southeast Asia.

HTA Ltd. helps build the road from investment to health technology, to healthcare – in a professional, conscious, competent and qualitative way, complying with scientific standards, aiming at making the healthcare systems better and efficient.


To make healthcare systems better and efficient by using evidence-based and value-based approach in everything we do.

What we do

НТА Ltd. offers health technology assessment:

  • HTA dossiers
  • Pharmacoeconomic analyses
  • Pharmacoeconomic analyses for negotiations with more powerful
  • Risk sharing agreements
  • Real world data (RWD)
  • Patient flows
  • Screening analyses
  • Model-based screening program designs
  • Relative effectiveness assessments (RЕАs) with randomised clinical trials (RCT) data and RWD
  • Health-related quality of life (HRQoL) measurement and analyses with local data
  • Local EQ-5D utility data
  • Early negotiations and consulting
  • Investment assessment
  • Trainings and educations – HTA, PE, epidemiology, biostatistics, pricing strategies, RSA
  • Health policy advisory
  • Regulations and legislations
  • Scientific publications (scientific journal articles, teaching resources and education books co-authorship in HTA guidelines)

HTA Ltd. is certified under BDS EN ISO 9001:2015  and ISO/IEC 27001:2013 standards

ISO 9001:2015 Quality management system:

  • Achieves higher operating efficiency;
  • Quality of HTA Ltd. products and services are clear, measurable and controllable; over time
  • Increases the quality of HTA Ltd. services and raises HTA Ltd. team’s awareness;
  • Ensures clear processes and (communication) structures, tasks and responsibilities throughout the entire organization;
  • An annual risk assessment;

ISO/IEC 27001:2013 Information security management systems:

  • Keeps and manages confidential information secure;
  • Monitoring security rules for internal data;
  • Increases the quality of HTA Ltd. services and raises HTA Ltd. team’s awareness;
  • Protected information from getting into unauthorized hands;
  • Ensured information is accurate and can only be modified by authorized users;
  • Assessed the risks and mitigated the impact of a breach;
  • Manages and minimizes risk exposure

We aim to provide our clients with professional assessment, based on our knowledge of health technologies, our access to the pharmaceutical and healthcare sector, and our fair business approach. We crucially rely on our experience, constant learning culture, and vast network of universities, experts and associates.

HTA Ltd. is also certified from Commission for Personal Data Protection.

Our team

Dr. Slaveyko Djambazov, PhD

Founder and Managing Partner

George Slavchev, PhD

Partner and Scientific Director

Adriana Dacheva

Partner and Operations Director

Diana Raleva

HTA analyst

Maya Hadzhieva

PhD, Scientific Analyst

Radoslava Mitova

MD, Medical Advisor

Marta Encheva

PhD, Scientific Analyst

Andrey Filipov

HTA Analyst

Ekaterina Pavlova

HTA Analyst

Yoanna Vutova

Marketing Specialist

HTA Ltd. Is a consulting company:

  • health technology assessment: drugs, medical devices, and diagnostic methods
  • healthcare management
  • health policy advisory
  • management consulting
  • investment consulting
  • market access strategy providing scientific advice
  • strategic pricing
  • pricing & reimbursement

By interacting and analyzing accordingly, HTA Ltd. provides a professional and objective assessment and advice.

НТА Ltd. Offers health technology assessment:

  • assessment with regard of the policies in the sphere of scientific research, which deals with short-term as well as the long- term results of the applied health technologies
  • provides information regarding alternative health strategies
  • systematically assesses the technical characteristics, the safety, clinical efficacy, and real life effectiveness, costs, social, legal and ethical consequences of the health technologies
  • focuses on the clinical and economic added value of the health technology

НТА Ltd. Offers health technology assessment:

  • analysis of the health problem
  • comparative analysis of the therapeutic efficacy and safety of the product
  • analysis of the pharmacoeconomic indicators
  • analysis of the budget impact

НТА Ltd. Offers advanced RWD analytics

  • Drug analyses by therapeutic indications and line of treatment
  • RWD cancer analytics
    • Real life patterns of progression free survival (PFS)
    • Mean/median dose of treatment
    • Duration of treatment (DoT)
    • Time to tumor progression (TTP)
    • Time to treatment failure (TTF)
    • Assessment of treatment algorithm by therapeutic indications (treatment sequencing)
  • Patient flows with RWD and analytics
  • Epidemiological analyses

НТА Ltd. Offers health technology assessment:

НТА Ltd. offers cost-effectiveness analyses with local data for quality of life:

  • Application of Bulgarian population norms results and local EQ-5D utility data in pharmacoeconomic analyses


PFIZER strongly recommends Health Technology Assessment Ltd. (HTA Ltd.) Bulgaria as a reliable provider of health technology assessment services, on time, within budget. Through its work in partnership with HTA Ltd., PFIZER aims to ensure reliable and comprehensive data and professional analysis on its products.
As a big pharmaceutical company, we strongly rely on the precise analysis of our products. When it comes to the Bulgarian market, we rely on HTA Ltd. for providing us with reliable, well-organized and detailed reports. That is why we would strongly recommend them to any potential clients in Bulgaria. The professional level is higher than expected and satisfies Novartis’ standards and requirements.
HTA Ltd. is a team of professionals with an extensive network of prominent experts, and their job is impressive. HTA Ltd. is a trusted partner and meets Sanofi’s high standards and requirements.
Eli Lily Bulgaria believes that the health technology assessment of products must be executed by specialists and experts who are familiar with the Bulgarian and the international regulations and market environment, with the necessary qualification for fulfilling such tasks, and who have the skills to analyze all information in a professional way and within the agreed time framework. For that reason Eli Lily​ recommends the services of HTA Ltd. for providing HTA support in preparation of analyses of medicinal products.
We, at Merck Bulgaria EAD, rely on HTA Ltd., which managed to provide a precisely written and detailed HTA report, for a less than a month, which was evaluated with a positive recommentation by the Health Technology Assessment Commission, three months later. After our work with HTA Ltd. we would strongly recommend their services as detailed, accurate, and within the agreed time framework.
Merck Bulgaria EAD
Positive Health Technology Assessment is a key step in successful market entry for medicinal products. Conducting qualitative and precise pharmacoeconomic analysis could sometimes be very challenging, especially in short terms. We trust HTA Ltd. to produce the pharmacoeconomic analysis of AbbVie’s products because we receive professional service within the specified term. We strongly recommend HTA Ltd. as a reliable partner with high standards of work.
Strategic launch plans of Medis Pharma Bulgaria have been greatly enhanced by our collaboration with HTA Ltd. HTA Ltd. delivered timely, evidence- based reimbursement dossier for submission of one of our products, which is the first in its class for the symptomatic treatment of blepharospasm, cervical dystonia of a predominantly rotational form (spasmodic torticollis) and spasticity of the upper limb. With their scientific and analytical expertise, we found the HTA Ltd. team to be dedicated and insightful, having met the expectations of this demanding project
Medis Pharma
Our company strives to qeliver the best medical solutions for patients in need, including patients with mental health issues. HTA Ltd. helps us achieve our mission in Bulgaria through its team of professionals who rovide unmatched clinical and pharmacoeconomic expertise when assessing our pharmaceutical products. Working
with HTA Ltd. is both very enjoyable and unquestionably fruitful.
Working with HTA Ltd. has been an incredibly productive endeavour. HTA Ltd. offers interactive project developments, customized to our needs, to assure the highest quality of health technology assessments of our medical devices. Their analyses feature thorough scientific, clinical, ethical, and economic solutions that shape the developing medical landscape of Bulgaria.
Our varied portfolio often requires an individualized approach. HTA Ltd. offers tailored and innovative solutions distinguished by superb quality. Their professional team always delivers without ever sacrificing excellence and does so in a timely fashion, having never missed a deadline. We strongly recommend working with HTA Ltd.
MSD Bulgaria
HTA Ltd. was found in 2015 as a consulting company and during its presence at Bulgarian market so far, they added a significant value to healthcare management and market access services. HTA Ltd. is a well-known and highly regarded company and based on their academic expertise they are one of the leaders in the fields of transfer and adaptation of HTA dossiers and pharmacoeconomic analysis, real-world data and educational programs. They have gained an outstanding track record, as well as a reputable image of a reliable business partner with an experienced approach.

Moreover, the presence of HTA Ltd. has helped the institutions of high professional standards in the Bulgarian market which undoubtedly is a significant achievement and credential to their commitment to business ethics and work ethic live up to the highest of standards.

We highly recommend HTA Ltd. for health technology assessment and pleased by their professionalism, we are looking forward to future collaborations.

Astellas Pharma

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Clinical trials –
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Good Practices –
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